Google
×
AllImagesVideosNews Maps Shopping Books
Search tools

Severe inflammation in new-borns induces long-term cognitive impairment by activation of IL-1β/KCC2 signaling during early development

BMC Medicine
Neonatal sepsis can induce long-term cognitive impairment in adolescence or adulthood, but the underlying molecular mechanism is not fully...
29 months ago

Population connectivity shapes the distribution and complexity of chimpanzee cumulative culture

Science | AAAS
Although cumulative culture is a hallmark of hominin evolution, its origins can be traced back to our common ancestor with chimpanzees.
1 month ago

Circulating Tumor DNA Is Capable of Monitoring the Therapeutic Response and Resistance in Advanced Colorectal Cancer Patients Undergoing Combined Target and Chemotherapy

Frontiers
Colorectal cancer (CRC) is a highly lethal disease worldwide. The majority of patients receiving targeted therapy or chemotherapy develop...
57 months ago

Modeling acute myocardial infarction and cardiac fibrosis using human induced pluripotent stem cell-derived multi-cellular heart organoids

Nature
This study focuses on generating self-organizing heart organoids (HOs) using human-induced pluripotent stem cells (hiPSCs).
8 months ago

Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission

Frontiers
The K-Cl co-transporter KCC2 plays multiple roles in the physiology of central neurons and alterations of its function and/or expression are associated with...
6 months ago

Development and regulation of chloride homeostasis in the central nervous system

Frontiers
γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter of the mature central nervous system (CNS). The developmental switch of GABAergic...
6 months ago

Florian Marku demands 'give me Amir Khan' after stopping Chris Jenkins

Sky Sports
Florian Marku retained the IBF International welterweight title and immediately turned his attention to some of the biggest names in the...
33 months ago

The burgeoning reach of animal culture

Science | AAAS
Today, there is no doubt that culture is widespread among animal species, both vertebrates and invertebrates, marine and terrestrial.
45 months ago

Risk Factors In Implant Dentistry: Unrestorable Implants

Oral Health Group
This article will review some of the situations resulting in unrestorable implants as well as their treatment, and will include several clinical examples.
65 months ago

Molecular and evolutionary insights into the structural organization of cation chloride cotransporters

Frontiers
Cation chloride cotransporters (CCC) play an essential role for neuronal chloride homeostasis. K+-Cl− cotransporter (KCC2), is the principal Cl−-extruder,...
6 months ago