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On the nature based flood defence dilemma and its Resolution: A game theory based analysis
ScienceDirect.com
We have looked into the complexities of nature-based flood defence implementation and its resolutions, modelling decision-making situations using game theory.
58 months ago
Identification of KCC2 Mutations in Human Epilepsy Suggests Strategies for Therapeutic Transporter Modulation
Frontiers
Epilepsy is a common neurological disorder characterized by recurrent and unprovoked seizures thought to arise from impaired balance between neuronal...
6 months ago
Comparing low volume of blood flow restricted to high-intensity resistance training of the finger flexors to maintain climbing-specific strength and endurance: a crossover study
Frontiers
This study aimed to compare the effects of high-intensity training (HIT) and low-intensity training with blood flow restriction (LIT + BFR) of the finger...
15 months ago
Dexterous Manipulation for Multi-Fingered Robotic Hands With Reinforcement Learning: A Review
Frontiers
Our purpose is to present a comprehensive review of the techniques for dexterous manipulation with multi-fingered robotic hands.
6 months ago
Role of NKCC1 and KCC2 in Epilepsy: From Expression to Function
Frontiers
As a main inhibitory neurotransmitter in the central nervous system, γ-aminobutyric acid (GABA) activates chloride-permeable GABAa receptors (GABAa Rs) and...
11 months ago
Anion transport and GABA signaling
Frontiers
Whereas activation of GABAA receptors by GABA usually results in a hyperpolarizing influx of chloride into the neuron, the reversed chloride driving force...
6 months ago
A novel pathogenic SLC12A5 missense variant in epilepsy of infancy with migrating focal seizures causes impaired KCC2 chloride extrusion
Frontiers
The potassium-chloride co-transporter 2, KCC2, is a neuron-specific ion transporter that plays a multifunctional role in neuronal development.
6 months ago
Neto2-null mice have impaired GABAergic inhibition and are susceptible to seizures
Frontiers
Neto2 is a transmembrane protein that interacts with the neuron-specific K+-Cl− cotransporter (KCC2) in the central nervous system (CNS).
6 months ago
Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophrenia
Frontiers
Many encoded gene products responsible for neurodevelopmental disorders (NDs) like autism spectrum disorders (ASD), schizophrenia (SCZ),...
6 months ago
Disruption of Slc4a10 augments neuronal excitability and modulates synaptic short-term plasticity
Frontiers
Slc4a10 is a Na+-coupled Cl−-HCO3− exchanger, which is expressed in principal and inhibitory neurons as well as in choroid plexus epithelial...
114 months ago